The Distribution of Guanine-Cytosine Pairs in Adenovirus DNAs
نویسندگان
چکیده
منابع مشابه
Investigation of Substituent Effects on the Strength of Hydrogen Bond in the Guanine: Cytosine Base Pairs: A Theoretical Study
In the present work, the substituent effect on the strength of H-bonds in the guanine – cytosine base pair was studied when the substituents are connected to the guanine base through a phenyl ring. In this study, guanine was substituted in the H8 and H9 positions by electron donating (ED) and electron withdrawing (EW) groups mediated by a phenyl ring in the gas phase. The calculations were perf...
متن کاملInfrared Signatures of Proton Transfer in Guanine⋅Cytosine and Adenine⋅Thymine Base Pairs: DFT Study
The structures of all stable tautomers of guanine⋅cytosine and adenine⋅thymine Watson–Crick base pairs produced by single and double proton transfers from the most stable structures are optimized using density functional theory (DFT) at the B3LYP/6-31G(d,p) level. The zwitterionic tautomer of guanine⋅cyosine is stable in a high-dielectric medium (water), but not in the gas phase. Normal mode ca...
متن کاملThe deprotonated guanine-cytosine base pair.
Awareness of the harmful effects of radiation has increased interest in finding the mechanisms of DNA damage. Radical and anion formation among the DNA base pairs are thought to be important steps in such damage [Collins, G. P. (2003) Sci. Am. 289 (3), 26-27]. Energetic properties and optimized geometries of 10 radicals and their respective anions derived through hydrogen abstraction from the W...
متن کاملTautomeric selectivity of the excited-state lifetime of guanine/cytosine base pairs: the role of electron-driven proton-transfer processes.
The UV spectra of three different conformers of the guanine/cytosine base pair were recorded recently with UV-IR double-resonance techniques in a supersonic jet [Abo-Riziq, A., Grace, L., Nir, E., Kabelac, M., Hobza, P. & de Vries, M. S. (2005) Proc. Natl. Acad. Sci. USA 102, 20-23]. The spectra provide evidence for a very efficient excited-state deactivation mechanism that is specific for the ...
متن کاملMicrohydration of Guanine base pairs.
We report spectroscopy of clusters of guanine base pairs with one and two water molecules. We recorded the vibronic spectra of the mass-selected GG(H2O) and GG(H2O)2 clusters using resonant two photon ionization (R2PI) and we used IR-UV double resonance spectroscopy to obtain ground state IR spectra of these clusters. We found that a single water molecule stabilizes one of two structures we had...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1981
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-54-2-425